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Dr. Michele Hargittai

Michele Hargittai

Title: Assistant Professor
School: Sciences
Academic Department: Chemistry
Phone: 814-472-2775
E-mail: mhargittai@francis.edu
Office Location: Sullivan 316
Additional Contact Information: Monday: 12:00pm - 2:00 pm Friday: 11:00am - 1:00 pm

Education

  • B.S. in Chemistry, Illinois State University
  • Ph.D. in Biochemistry, Molecular Biology, and Biophysics, University of Minnesota
  • Postdoctoral Research Associate, Pennsylvania State University

Biography

Current and Upcoming Courses:

  • CHEM 103 Human Chemistry I
  • CHEM 201L Organic Chemistry I Lab

Courses Taught:

  • CHEM 103  Human Chemistry I
  • CHEM 104  Human Chemistry II
  • CHEM 201L Organic Chemistry I Lab
  • CHEM 202L Organic Chemistry II Lab
  • BIOL   305    Immunology

Research Interests:

  • Viral replication
  • Mitochondrial Transcription

Publications/Awards:

  • 1. Hargittai M. R. S., Cameron C. E., The Hepatitis C Virus NS5A protein inhibits PKR activation. in preparation
  • 2. Hargittai M. R. S, Hwang J., Cameron C. E., PKA phosphorylation regulates nuclear localization of the Hepatitis C Virus NS5A protein. in preparation
  • 3. Pathak H. B., Arnold J. J., Wiagand P. N., Hargittai M. R. S., Cameron C. E., Picornavirus genome replication: Assembly and organization of the VPg uridylylation ribonucleoprotein (initiation) complex. (2007) J Biol Chem, 282, 16202-16213.
  • 4. Huang L., Hwang J., Sharma S. D., Hargittai M. R. S., Chen Y., Arnold J. J., Raney K. D., Cameron, C. E. Hepatitis C virus nonstructural protein 5A (NS5A) is an RNA-binding protein. (2005) J Biol Chem 280, 36417-28.
  • 5. Huang L., Sineva E. V., Hargittai M. R. S., Sharma S. D., Suthar M., Raney K. D., Cameron, C. E. Purification and characterization of hepatitis C virus non-structural protein 5A expressed in Escherichia coli. (2004) Protein Expr Purif 37, 144-53.
  • 6. Hargittai M. R. S., Gorelick R. J., Rouzina I., Musier-Forsyth K.Mechanistic Insights into the Kinetics of HIV-1 Nucleocapsid Protein-Facilitated tRNA annealing to the Primer Binding Site. (2004) J Mol Biol 337, 951-68.
  • 7. Hargittai M. R. S., Mangla A. T., Gorelick R. J., Musier-Forsyth K. Terbium Cleavage Assays Reveal tRNALys,3 Structural Changes Induced by the HIV-1 Nucleocapsid Protein. (2001) J Mol Bio 312, 985-97.
  • 8. Hargittai M. R. S., Musier-Forsyth K. Use of Terbium as a Probe of tRNA Tertiary Structure and Folding. (2000) RNA 6, 1672-80.

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