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Dr. Michele Hargittai

Michele Hargittai

Title: Associate Professor
School: Sciences
Academic Department: Chemistry
Phone: 814-472-2775
E-mail: mhargittai@francis.edu
Office Location: Science Center 212
Additional Contact Information: Monday: 12:00pm - 2:00 pm Friday: 11:00am - 1:00 pm


  • B.S. in Chemistry, Illinois State University
  • Ph.D. in Biochemistry, Molecular Biology, and Biophysics, University of Minnesota
  • Postdoctoral Research Associate, Pennsylvania State University


Research & Teaching

Research Interests

  • Viral replication
  • Mitochondrial Transcription

Current and Upcoming Courses

  • CHEM 103 Human Chemistry I
  • CHEM 201L Organic Chemistry I Lab

Courses Taught

  • CHEM 103  Human Chemistry I
  • CHEM 104  Human Chemistry II
  • CHEM 201L Organic Chemistry I Lab
  • CHEM 202L Organic Chemistry II Lab
  • BIOL 305  Immunology
  • CHEM 404 Bioorganic Chemistry
  • CHEM 410 Advanced Organic Mechanisms
  • CORE 113 Symmetry in Nature
Publications & Awards


  • 1.Cordek, D.G., Croom-Perez-, T.J., Hwang, J., Hargittai, M.R.S., Subba-Reddy, C.V., Han, Q., Lodeiro, M.F., Ning, G., McCrory, T.S., Arnold, J.J., Koc, H., Lindenbach, B.D., Showalter, S.A., Cameron, C.E. Expanding the proteome of an RNA virus by phosphorylation of an intrinsically disordered viral protein. (2014) J Biol Chem, 289 (35), 24397-416. 
  • 2. Lipski, M., McConnell, L. E., Grabowski, L.E., Ritchey, K.N., Hargittai, M.R.S., Hargittai, B. Synthesis and characterization of azo dyes. (2014) Spectrum: Journal of Student Research at Saint Francis University, 5 (1), 9-16.  
  • 3. Kline, K.M.; Harteis, H.J.; McConnell, L.E.; Jesberger, J.A.; Hargittai, M.R.S.; Hargittai, B. "The influence of multiple prolines on the folding disulfide rich small peptides" Spectrum: Journal of Student Research at Saint Francis University,(2012) 2, 38-43.
  • 4. Rust, H.l.; Kline, K.M.; Harteis, K.J.; Hargittai, M.R.S.; Hargittai, B. "The Influence of proline on the folding of contoxins" J. Undergrad Chemistry Research, (2012) 11, 50-52.  
  • 5.Hargittai, M.R.S.; Harteis, H.J.; Kline, K.M.; Hargittai, B. "Role of Proline in the Folding of Conotoxins" Biophysics Journal. (2010) 98, 32a
  • 6. Pathak H. B., Arnold J. J., Wiagand P. N., Hargittai M. R. S., Cameron C. E., Picornavirus genome replication: Assembly and organization of the VPg uridylylation ribonucleoprotein (initiation) complex. (2007) J Biol Chem, 282, 16202-16213.
  • 7. Huang L., Hwang J., Sharma S. D., Hargittai M. R. S., Chen Y., Arnold J. J., Raney K. D., Cameron, C. E. Hepatitis C virus nonstructural protein 5A (NS5A) is an RNA-binding protein. (2005) J Biol Chem 280, 36417-28.
  • 8. Huang L., Sineva E. V., Hargittai M. R. S., Sharma S. D., Suthar M., Raney K. D., Cameron, C. E. Purification and characterization of hepatitis C virus non-structural protein 5A expressed in Escherichia coli. (2004) Protein Expr Purif 37, 144-53.
  • 9. Hargittai M. R. S., Gorelick R. J., Rouzina I., Musier-Forsyth K.Mechanistic Insights into the Kinetics of HIV-1 Nucleocapsid Protein-Facilitated tRNA annealing to the Primer Binding Site. (2004) J Mol Biol 337, 951-68.
  • 10. Hargittai M. R. S., Mangla A. T., Gorelick R. J., Musier-Forsyth K. Terbium Cleavage Assays Reveal tRNALys,3 Structural Changes Induced by the HIV-1 Nucleocapsid Protein. (2001) J Mol Bio 312, 985-97.
  • 11. Hargittai M. R. S., Musier-Forsyth K. Use of Terbium as a Probe of tRNA Tertiary Structure and Folding. (2000) RNA 6, 1672-80.

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