Dr. Pedro Muiño
Title: Professor, Physical Chemistry
Academic Department: Chemistry
Office Location: Science Center 210
Office Hours: Tuesday: 9:00 - 11:00 Wednesday: 2:00 - 3:00 Thursday: 9:00 - 11:00
Additional Contact Information:
- B. Sc. in Chemistry, University of Santiago (Spain)
- Ph. D. in Physical Chemistry, Montana State University
- Postdoctoral Research Associate, University of Washington
- Chemical Principles I and Chemical Principles II
- Human Chemistry I and Human Chemistry II
- Dynamics and Quantum Mechanics
- Introduction to Astrophysics
- Computational and Mathematical Methods in Science
- Other courses: The Science of Star Trek, Food Science
Academic Career Information
- Dean of General Education (2012- Present)
- Professor of Chemistry, Saint Francis University (2009-Present)
- Research Integrity Officer, Saint Francis University (2009-2014)
- Associate Professor of Chemistry, Saint Francis University (2003-2009)
- Investigative Scientist, Office of the Inspector General, National Science Foundation (2008)
- Visiting Research Professor, Montana State University (Summer 2002-2006)
- Assistant Professor of Chemistry, Saint Francis University (2000-2003)
- Assistant Professor of Chemistry, Kansas State University (1995-2000)
Research & Publications
- Mechanism of fluorescence quenching of tryptophan in proteins
- Molecular Folding of conotoxins
- Chemical Education
Selected Recent Publications
- 42. Jianhua Xu, Binbin Chen, Patrik Callis, Pedro L. Muíño, Henriëtte Rozeboom, Jaap Broos, Dmitri Toptygin, Ludwig Brand and Jay R. Knutson. Picosecond Fluorescence Dynamics of Tryptophan and 5-Fluorotryptophan in Monellin: Slow Water–Protein Relaxation Unmasked J. Phys. Chem. B2015, 119, 4230–4239. doi:10.1021/acs.jpcb.5b01651
- 40. Arianna Biesso, Jianhua Xu, Pedro L. Muíño, Patrik R. Callis and Jay R. Knutson. Charge Invariant Protein-Water Relaxation in GB1 via Ultrafast Tryptophan Fluorescence. J. Am. Chem. Soc. 2014, 136, 2739-2747. doi:10.1021/ja406126a
- 38. Brittany A. Kovacs and Pedro L. Muíño. Molecular Modeling of Folding in Lactam-Modified α-Conotoxins. Spectrum. 2014, 4, 4-8.
- 34. Aaron P. Osysko and Pedro L. Muíño. Fluorescence quenching of tryptophan and trypotophanyl dipeptides in solution. J. Biophys. Chem. 2011, 2, 316-321. doi:10.4236/jbpc.2011.23036
- 33 Chia-PinPan, Pedro L. Muíño, Mary Barkley, and Patrik R. Callis. Understanding Wavelength Dependence of Tryptophan Fluorescence Decays. J. Phys. Chem. B.2011, 115, 3245-3253. doi:10.1021/jp111925w
- 28. Pedro L. Muíño and Patrik Callis. Solvent Effects on the Fluorescence Quenching of Tryptophan by Amides via Electron Transfer. Experimental and Computational Studies. J. Phys. Chem. B. 2009, 113, 2572-2577. doi:10.1021/jp711513b
- 27. Patrik R. Callis, Alexander Petrenko, Pedro L. Muíño, Ramón Tusell. Ab Initio Prediction of Tryptophan Fluorescence Quenching by Protein Electric Field-Enabled Electron Transfer. J. Phys. Chem. B. 2007, 111, 10335-10339. doi:10.1021/jp0744883
- 23. Khaled A. Khatib, Thomas J. Herald, and Pedro L. Muíño. Application of fluorescence spectroscopy to characterize soybean varieties. Int. J. Food Sci. Tech. 2005, 40, 545-555. doi:10.1111/j.1365-2621.2005.00974.x
- 22. Pedro L. Muíño. The OH• + CH3SH Reaction: Support for an Addition-Elimination Mechanism from Ab Initio Calculations. J. Comp. Chem. 2005, 26, 612-618. doi:10.1002/jcc.20195
- 21. P. L. Muíño, A. M. Thompson, and R. J. Buenker. Use of time-correlated single photon counting detection to measure the speed of light in water. Khim. Fiz. 2004, 23, 117-128. arXiv:physics/0502100
- 20. R.J. Buenker, P. L Muíño. Quantum Mechancial Relations for the Energy, Momentum and Velocity of Single Photons in Dispersive Media. Khim. Fiz. 2004, 23, 111-116. arXiv:physics/0607094
Talks & Presentations
- 34. Pedro L. Muíño and Patrik R. Callis. Parallels between Enzyme Action and Tryptophan Fluorescence Brightness in Proteins. 59th Annual Meeting of the American Biophysical Society. Baltimore, MD. February 7-11, 2015.
- 33. Pedro L. Muíño, J. Nathan Scott and Patrik R. Callis. Fine-Grained Spatial and Temporal Resolution of Water and Protein Contributions to Ultra-Fast and Slower Fluorescence Shifts from MD + QM Simulations. 58th Annual Meeting of the American Biophysical Society. San Francisco, CA. February 15-19, 2014.
- 32. Arianna Biesso, Pedro L. Muíño, Jianhua Xu, Patrik R. Callis and Jay R. Knutson. Tryptophan Fluorescence in GB1: Nanosecond Dynamics Strongly Depend on pH, While 30ps Relaxation is Constant. 57th Annual Meeting of the American Biophysical Society. Philadelphia, Pennsylvania. February 2-6, 2013.
- 31. Aaron P. Osysko and Pedro L. Muíño. Effect of pH on Fluorescence quenching of tryptophan and tryptophanyl dipeptides in solution. 57th Annual Meeting of the American Biophysical Society. Philadelphia, Pennsylvania. February 2-6, 2013.
- 30.Molecular Modeling of Folding in Lactam-Modified (Glutamate+Lysine Analog) Conotoxins. Christopher R. DeLaney and Pedro L. Muíño. 56th Annual Meeting of the American Biophysical Society. San Diego, California. February 25-29, 2012.
- 29. Sabbatical-Based Inreach to OIG from the Research Community. Kenneth L. Busch and Pedro L. Muíño. 241st American Chemical Society National Meeting. Anaheim, California. March 27-31, 2011.
- 28. Modeling the Effect of Side-Chain Length on the Folding of Lactam-Modified Conotoxins. Aaron P. Osysko, Brittany S. Kovacs, Christopher R. DeLaney, and Pedro L. Muíño. 55th Annual Meeting of the American Biophysical Society. Baltimore, Maryland. March 5-9, 2011.
- 27. Molecular Modeling of Folding in Lactam-Modified α-Conotoxins. Brittany A. Kovacs, Aaron Osysko and Pedro L. Muíño. 54th Annual Meeting of the American Biophysical Society. San Francisco, California. February 20-24, 2010.
- 26. Understanding Wavelength Dependence of Tryptophan Fluorescence Decays. Chia-Pin Pan, Pedro L. Muíño, Mark Barkley, and Patrik R. Callis. 54th Annual Meeting of the American Biophysical Society. San Francisco, California. February 20-24, 2010.
Recent Invited Talks
- 24. Service-Research-Learning in the Bolivian Andes. Faculty Development Committee Presentation at Saint Francis University. Loretto, PA. November 7, 2013.
- 23. The Amino Acid Tryptophan as a Probe of Protein Structure: How to explain the quantum yield in protein spectroscopy. Universidade de A Coruña, Spain. June 12, 2013.
22.Research Integrity Oversight: A view from within the system. University of Pittsburgh. Pittsburgh, PA. Ethics Forum. June 24, 2011.
21.Why Research Integrity Matters to You. Duquesne University. Pittsburgh, PA. June 3, 2011.
20. Responding to Academically Adrift: What Colleges Can Do. Saint Francis University Faculty Development Week. Loretto, PA. May 10, 2011.
19. Educating Students in Responsible Professional Practices in Research. STEP Workshop for first and second year students. Loretto, PA. June 11, 2008.
- 18. Ensuring Responsible Professional Practices in Research. Saint Francis University Faculty Development Week. Loretto, PA. May 6, 2008.
- 17. Solving Global Warming. Saint Francis University Connections program. Loretto, PA. March 28, 2007.
- 16. Molecular Modeling of Protein Fluorescence: getting information on protein shapes from light emission. Saint Francis University. Loretto, PA. November 16, 2006.
- 15. Tryptophan as a Probe of Protein Structure. Centro de Química-Física Molecular. Instituto Superior Técnico. Lisbon, Portugal. May 30, 2005.
Affiliations & Service
- Program Reviewer (Chemistry-Sec. Ed.) for the Pennsylvania Department of Education
- Member of the Education Committee of the Biophysical Society
- Regional Director for Kappa Mu Epsilon
- Member of Penn-Mont Academy Board of Directors
- Journal Reviewer
- Journal of Physical Chemistry
- Journal of Fluorescence
- Journal of Chemical Education
- The Chemical Educator
- Structural Chemistry
- Reviewer for the National Science Foundation